Comparative Internal Medicine Laboratory

IMG_1172-toned-lr-headerThe missions of the Comparative Internal Medicine Laboratory are to:

  • Investigate diseases relevant to people and animals,
  • Develop tools for the practical diagnosis, treatment and prevention of disease, and
  • Train the next generation of medical specialists in scientific methodology while conducting ethical, translational research.


Executive Board

Director: Carol R. Reinero, DVM, PhD, DACVIM (SAIM)
900 E. Campus Drive
Columbia, Missouri 65211

Associate Director: Amy E. DeClue, DVM, MS, DACVIM (SAIM)
900 E. Campus Drive
Columbia, Missouri 65211

Laboratory Manager: Hans Rindt, PhD
W168 Veterinary Medicine Building
Columbia, Missouri 65211


IMG_1218-toned-lrPrimary Investigators

Leah A. Cohn, DVM, PhD, DACVIM-Small Animal Internal Medicine
Microbiology (e.g., MRSA, C. felis and sepsis), immunology (e.g., inflammation and allergic airway disease) and clinical treatment trials (e.g., cytauxzoonosis, asthma)

Amy E. DeClue, DVM, MS, DACVIM-Small Animal Internal Medicine
Immunology with a focus on innate immunity, cell culture, use of small and large animal models of disease (sepsis, acute respiratory distress syndrome, systemic inflammatory response syndrome) for translational research, clinical research (innate and adaptive immunity, sepsis, systemic inflammatory response syndrome)

John R. Dodam, DVM, MS, PhD, DACVAA
Cellular and in vivo physiology, clinical trials in large and small animal models

Vamsi Guntur, MD
Early detection of lung tumors using targeted diagnostics and airway biomarkers, with current focus on common features between inflammatory and neoplastic airway diseases

Meghan Harmon, DVM, DACVECC
Coagulation pathways and small animal critical care medicine

Philip J. Johnson, BVSc, MS, MRCVS, DACVIM-Large Animal Internal Medicine, DECEIM
Immunology (inflammation), sepsis (endotoxemia), equine microbiome, and identification of pathophysiological processes in equine laminitis

Marie E. Kerl, DVM, MPH, DACVIM-Small Animal Internal Medicine, DACVECC
Clinical trials coordination, prevention of hospital-associated morbidity, statistical analysis

John R. Middleton, DVM, PhD, DACVIM-Large Animal Internal Medicine
Bovine mastitis, staphylococci, clinical microbiology, epidemiology, molecular speciation and fingerprinting of bacteria

Patrick Pithua, BVetMed, MSc, PhD
Applied research in calf health management, prevention and control of Mycobacterium avium subsp. paratuberculosis

Carol R. Reinero, DVM, PhD, DACVIM-Small Animal Internal Medicine
Use of a feline allergic asthma model for comparative and translational research (therapeutic trials, development of novel non-invasive diagnostics, dissecting mechanisms of immunomodulation); clinical immunology and pulmonology; characterization of the respiratory microbiota in health and disease


Graduate Students

Pamela R.F. Adkins, DVM, MS, DACVIM-Large Animal Internal Medicine (PhD candidate)

Christa Bernhard, DVM (MS candidate)

Véronique Bernier Gosselin, DVM, MSc (PhD candidate)

Megan Grobman, DVM, MS (PhD candidate)

Diana Hoffman, DVM (MS candidate)

Aida Vientós-Plotts, DVM (MS candidate)


Undergraduate Student

Kaitlin Bishop


Laboratory Technician

Juliana Amorim


DSC_6607_alt-kcGiving to the Comparative Internal Medicine Laboratory

The Comparative Internal Medicine Laboratory needs your financial support to fund cutting-edge research to help animals with a variety of medical problems and to train the next generation of veterinary scientists.

Past gifts have helped support studies with significant impacts on the health of animals and people. Some of these include:

  • New and better treatments for feline asthma and chronic bronchitis
  • Improved treatment of immunologic disorders such as immune-mediated hemolytic anemia and immune mediated polyarthropathy
  • Better management of endocrine disorders including diabetes mellitus
  • Better options for the treatment of bobcat fever, sepsis and ehrlichiosis
  • Studies of the immune response to cancer
  • New and effective preventive treatments for equine laminitis

Gifts supporting the laboratory can be made in honor or in memory of a special person or pet. Please join us in our efforts to find cures for common diseases in both animals and people by making a donation today.

To make a gift online, visit our giving site. Please specify “CIML” in the Gift Instructions.

To make a gift by phone, call 573-882-0548.

To make a gift by mail, send your donation to:

IMG_1153-toned-lrAttn: Director of Advancement
MU College of Veterinary Medicine
Comparative Internal Medicine Laboratory Gift Fund
W210 Veterinary Medicine Building
Columbia, MO 65211

Please make your check payable to the University of Missouri. To ensure proper routing, please write “CIML” in the memo section of your check.

All donations are tax-deductible to the fullest extent allowed by law.

For further information, contact the College of Veterinary Medicine Advancement Office at or 573-882-0548.


Useful Links

University of Missouri

MU College of Veterinary Medicine

MU Department of Veterinary Medicine and Surgery

American College of Veterinary Internal Medicine